The Cell Death Research Hub (CDR-H) connects leading researchers across Belgian universities, including Ghent, Antwerp, and Leuven, to advance cutting-edge research in cell death.
We bring together a vibrant community to share expertise, foster collaborations, and drive innovation, while increasing the global visibility of Belgian research. Our network spans studies on the molecular mechanisms of cell death in health, disease, and stress, across both plant and animal systems.
Through this platform, you can explore ongoing research, discover career opportunities, follow our latest publications, and stay informed about events and meetings. We also actively build a strong community through scientific exchange, networking events, and outreach activities.
Join us and be part of a dynamic and growing research network.
Contact Peter Vandenabeele or Bruno Verstraeten to get involved.
Article: Ferroptosis inhibition enhances liver and lung graft function
Veeckmans et al. demonstrate that ischemia-reperfusion injury triggers an early lipid peroxidation wave in human transplants. They further show that pharmacological ferroptosis inhibition with FXT-001 suppresses lipid radical propagation, modulates iron homeostasis, and improves liver and lung graft function in
Article: BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states
A 3-Hydroxybutyrate dehydrogenase 2 (BDH2)-dependent mechanism that orchestrates inter-organelle Fe(II) transfer, linking metabolic regulation of lysosomal pH to the ferroptosis vulnerability of the mesenchymal, drug-tolerant cancer cells. This paper demonstrates that the mitochondrial protein BDH2 localizes at the mitochondrial-lysosomal contacts
Dr. Vishva Dixit to be awarded Ghent University Honorary Doctorate
On Thursday March 19th, Dr. Vishva Dixit will be awarded an honorary doctorate on behalf of Ghent University as a recognition of his outstanding sientific achievements. Dr. Vishva Mitra Dixit, born in 1956 in Kenya, is a Kenyan‑American physician and
Our Consortiums
Inflammasomes and Pyroptosis in Health and Disease
Phagocytosis in Inflammation and Tissue Repair
Cell Death and Inflammation: Immunogenic Cell Death and Cancer Immunotherapy
Cell Clearance in Health and Disease
Cell Death Investigation and Therapy Laboratory
Cell Death Signaling lab (University of Antwerp)
Recent Events
Article: Ferroptosis inhibition enhances liver and lung graft function
Veeckmans et al. demonstrate that ischemia-reperfusion injury triggers an early lipid peroxidation wave in human transplants. They further show that
Article: BDH2-driven lysosome-to-mitochondria iron transfer shapes ferroptosis vulnerability of the melanoma cell states
A 3-Hydroxybutyrate dehydrogenase 2 (BDH2)-dependent mechanism that orchestrates inter-organelle Fe(II) transfer, linking metabolic regulation of lysosomal pH to the ferroptosis
Dr. Vishva Dixit to be awarded Ghent University Honorary Doctorate
On Thursday March 19th, Dr. Vishva Dixit will be awarded an honorary doctorate on behalf of Ghent University as a
